The genetic architecture of adaptation in Clarkia
Line-cross experiments to dissect the architecture of fitness differences across populations
Using crosses between populations of Clarkia xantiana that span the species’ range, we’re decomposing fitness differences into their additive, dominance, and epistatic components, then linking these to the genetic basis of local adaptation. The work tests classical predictions about how the architecture of adaptation shapes the predictability — and reversibility — of evolutionary response to environmental change.